Secondary hemophagocytic lymphohistiocytosis
Immune system disordersNew in v6.0
- G1Asymptomatic or mild symptoms; requiring clinical and/or diagnostic evaluation; intervention not indicated
- G2Moderate symptoms; intervention indicated (e.g., immunosuppressive agents)
- G3Severe or medically significant but not immediately life threatening; hospitalization or prolongation of existing hospitalization indicated
- G4Life-threatening consequences; urgent intervention indicated
- G5Death
Definition and note
DefinitionA disorder characterized by the development of a pathological and biochemical hyperinflammatory syndrome characterized by fever, cytopenias, hyperferritinemia, coagulopathy, hypofibrinogenemia and/or transaminitis and is attributable to therapy.
MedDRA code (LLT): 10081409 · CTCAE v6.0 (NCI), original English text.