Autoimmune disorder
- G1Asymptomatic; serologic or other evidence of autoimmune reaction, with normal organ function; intervention not indicated
- G2Evidence of autoimmune reaction involving a non-essential organ or function (e.g., hypothyroidism)
- G3Autoimmune reactions involving major organ (e.g., colitis, anemia, myocarditis, kidney)
- G4Life-threatening consequences; urgent intervention indicated
- G5Death
Definition and note
DefinitionA disorder characterized by loss of function or tissue destruction of an organ or multiple organs, arising from humoral or cellular immune responses of the individual to his own tissue constituents.
Navigational notePrior to using this term consider specific autoimmune AEs.
MedDRA code (LLT): 10061664 · CTCAE v6.0 (NCI), original English text.