Thrombotic thrombocytopenic purpura
- G1Not applicable
- G2Not applicable
- G3Laboratory findings with clinical consequences (e.g., renal insufficiency, petechiae)
- G4Life-threatening consequences, (e.g., CNS hemorrhage or thrombosis/embolism or renal failure)
- G5Death
Definition and note
DefinitionA disorder characterized by a deficiency of ADAMTS13 and the presence of microangiopathic hemolytic anemia, thrombocytopenic purpura, fever, renal abnormalities and neurological abnormalities such as seizures, hemiplegia, and visual disturbances. It is an acute or subacute condition.
MedDRA code (LLT): 10043648 · CTCAE v6.0 (NCI), original English text.