Reversible posterior leukoencephalopathy syndrome
- G1Not applicable
- G2Moderate symptoms; limiting instrumental ADL or mild/moderate impact on age-appropriate normal daily activity (pediatric)
- G3Severe symptoms; hospitalization; limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
- G4Life-threatening consequences
- G5Death
Definition and note
DefinitionA disorder characterized by headaches, mental status changes, visual disturbances, and/or seizures associated with imaging findings of posterior leukoencephalopathy. It has been observed in association with hypertensive encephalopathy, eclampsia, and immunosuppressive and cytotoxic drug treatment. It is an acute or subacute reversible condition. Also known as posterior reversible encephalopathy syndrome (PRES).
MedDRA code (LLT): 10063761 · CTCAE v6.0 (NCI), original English text.