Retinoic acid syndrome
- G1Fluid retention; <3 kg of weight gain; intervention with fluid restriction and/or diuretics indicated
- G2Moderate signs or symptoms; steroids indicated
- G3Severe symptoms; hospitalization indicated
- G4Life-threatening consequences; ventilatory support indicated
- G5Death
Definition and note
DefinitionA disorder characterized by weight gain, dyspnea, pleural and pericardial effusions, leukocytosis and/or renal failure originally described in patients treated with all-trans retinoic acid.
MedDRA code (LLT): 10038921 · CTCAE v6.0 (NCI), original English text.