Palmar-plantar erythrodysesthesia syndrome
- G1Minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain
- G2Skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting instrumental ADL or mild/moderate impact on age-appropriate normal daily activity (pediatric)
- G3Severe skin changes (e.g., peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
- G4Not applicable
- G5Not applicable
Definition and note
DefinitionA disorder characterized by redness, marked discomfort, swelling, and tingling in the palms of the hands or the soles of the feet. Also known as Hand-Foot Syndrome.
MedDRA code (LLT): 10054524 · CTCAE v6.0 (NCI), original English text.