Optic neuritis
Nervous system disordersNew in v6.0
- G1Asymptomatic or mild symptoms; only enhancement on MRI scan with no change in vision
- G2Treatment indicated; best corrected visual acuity 20/40 and better or 3 lines or less decreased vision from known baseline in the affected eye; limiting instrumental ADL or mild/moderate impact on age-appropriate normal daily activity (pediatric)
- G3Severe or medically significant but not immediately sight-threatening; decrease in visual acuity (best corrected visual acuity worse than 20/40 or more than 3 lines of decreased vision from known baseline, up to 20/200) in the affected eye; oral steroids indicated; limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
- G4Sight-threatening consequences; urgent intervention indicated; best corrected visual acuity of 20/200 or worse in the affected eye: significant visual field loss; marked optic disc edema or enhancement on MRI scan; intravenous steroids indicated; blindness
- G5Not applicable
Definition and note
DefinitionA disorder characterized by inflammation and demyelination of the optic nerve that causes acute, usually monocular, visual loss.
MedDRA code (LLT): 10030942 · CTCAE v6.0 (NCI), original English text.