CTCAE RápidoAdverse event grades · CTCAE v6.0
  1. G1Not applicable
  2. G2Not applicable
  3. G3Asterixis; mild encephalopathy; drug-induced liver injury (DILI); limiting self-care ADL or severe impact on age-appropriate normal daily activity (pediatric)
  4. G4Life-threatening consequences; moderate to severe encephalopathy; coma
  5. G5Death
Definition and note

DefinitionA disorder characterized by the inability of the liver to metabolize chemicals in the body. Laboratory test results reveal abnormal plasma levels of ammonia, bilirubin, lactic dehydrogenase, alkaline phosphatase, aminotransferase, and/or prolongation of prothrombin time (INR.) Drug-induced liver injury (DILI) as defined by Hy's Law.

MedDRA code (LLT): 10019663 · CTCAE v6.0 (NCI), original English text.

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